Methodology
This is the production process behind every drug, comparison, and condition page on ClinIndex.
1. Source selection
We start with U.S. primary sources: the FDA for product approvals, prescribing information, and safety communications; DailyMed (U.S. National Library of Medicine) for the approved label of a specific product; MedlinePlus (also NLM) for patient-facing drug and condition reference; the NIH Office of Dietary Supplements for vitamins, minerals, and botanicals; NIDDK for digestive and metabolic conditions; LiverTox (NIH) for drug-induced liver injury risk; and the CDC for prevention and infection guidance. We cross-reference the BNF and NICE guidelines for additional dosing detail and interactions.
2. Drafting
A first draft is written from those sources. We use large language models to help structure and edit drafts; we do not use them to generate clinical claims that aren't traceable to a primary source.
3. Citation
Every clinical claim links inline to the primary source that supports it. The full source list appears at the bottom of each page. We do not rely on footer-only "see FDA" notes. Citations are tied to the specific claim they support.
4. Accuracy check
Every clinical claim in the draft is checked back against the primary source it cites, line by line, before the page publishes. Where the sources disagree or the evidence is thin, the page says so rather than picking a side. Pages are not reviewed by a named clinician, and we do not present them as clinical advice.
5. Dating
Each page records the date it was last reviewed and the date of its next scheduled review (12 months by default, sooner for fast-moving topics such as new FDA safety communications or label changes).
6. Re-review and changelog
Pages are re-checked against current primary sources on the next-review date, or sooner if a clinical guideline changes or a regulatory update lands (e.g., an FDA Boxed Warning addition). Changes are recorded in a per-page changelog for clinical updates only, not for typos or layout edits.